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The mouth is a gateway between our inside and the external world. 

When oral bacteria are left unchecked or grow out of control we get inflammation which triggers an immune response through the production of cytokines, chemokines and anti-microbial peptides.

FLORALIS
Bioactive oral spray reduces plaque & biofilm bacterias in the Oral Microbiota


 
There are about 700 kinds of microorganisms that exist in the human mouth, and these microbes constitute the human oral microbiota. It is one of the most complex microbial communities in the human body.   

FLORALIS reduces pathogenic oral bacteria, making the oral cavity less inviting for viruses.  This allows the oral microbiota and innate immune response to function at its best...

It's a simple approach and one I think is effective for general oral maintenance and especially for those with oral inflammation.

Honokiol and Magnolol has also been shown to inhibit CXCL10 and CXCL11 production in IL-27- stimulated human oral epithelial cells.  These cytokines play a part in severe cases of the COVID-19 infection. 

Viruses and bacteria thrive in an acidic environment, acidification is crucial for viral replication

The mouth is naturally a non-acidic environment.  Bacteria convert sugars into acids through a process called glycolysis.  The majority of viruses are acid-activated, meaning... viral membrane fusion depends on the exposure of the virus to low pH.Once a virus infiltrates the host, it leads indirectly to increased extracellular acidity. Our saliva plays an important role in modulating the oral microbiota and the clearance of pathogens. ​

 “An alkaline body can absorb up to 20 times more oxygen than an acidic body.” Dr Otto Warburg, a Nobel Prize Winner for his work on respiratory enzymes and cancer.

MAGNOLIA BARK EXTRACT RELATED STUDIES

Upper respiratory tract infections are probably the most common infections in the world. 

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Experts are looking at mouthwash to see if it can help stop the spread of COVID-19 

At the same time, some of these mouthwash solutions end up killing all bacterias and microorganism including beneficial bacteria in the host epithelial. And there are other problems with the idea. Like toxicity. And no solid science.
“Some of these agents, such as ethanol and hydrogen peroxide, may, if used several times a day over a period of two to three months, induce inflammation” in the mouth and throat, warned the British team, led by Valerie B. O’Donnell, director of the division of infection and immunity at Cardiff University School of Medicine.
One of the most common and extensively used oral antiseptic and antiplaque is Chlorhexidine Gluconate.  This is the same ingredient used in surgical hand scrub (do you really want this in your mouth?)  However, its long-term use is associated with a number of adverse side effects and kills all bacteria including beneficial bacteria in the host epithelial. [9] [9] https://pubmed.ncbi.nlm.nih.gov/26600203/


Magnolia Bark Extracts in a study was to be as effective as Chlorhexidine and without the toxicity. [6] [6] https://www.webmd.com/oral-health/news/20071116/magnolia-bark-extract-vs-bad-breath
 
Along with MBE, MAG7 is formulated with the extracts of natural phytochemicals from plants like Sage, Olive leaf, Plantain leaf, Artemisia Annua, Salvia Miltiorrhiza, OSHA/Ligusticum porteri to name few... all which have been studied for their pharmacological activities, which has been the focus of attraction for scientists

The airway epithelium is central to the defence of the lungs against pathogens.
It acts as a physical barrier against pollutants, pathogens and harmless inhaled particles from the external environment.  

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